|[Evolutionary Nanomaterials & Nanodevices] Daniel Rossi, Jae Hyo Han, Dongwon Yoo, Yitong Dong, Yerok Park, Jinwoo Cheon, and Dong hee Son
"Photoinduced Separation of Strongly Interacting 2-D Layered TiS2 Nanodiscs in Solution"
J. Phys. Chem. C., 118 (23), 12568-12573 (May 16, 2014) DOI : http://pubs.acs.org/doi/abs/10.1021/jp5038624
2-D layered, Transition metal dichalcogenide, TiS2, photoexcitation, pulsed laser
|[Nanobio Interface] Seong-Min Jo, Seung-hyun Noh, Zongwen Jin, Yongjun Lim, Jinwoo Cheon, and Hak-Sung Kim
"Simple and efficient capture of EGRF-expressing tumor cells using magnetic nanoparticles"
Sensors and Actuators B., 201 (1), 144-152 (May 10, 2014) DOI : https://www.sciencedirect.com/science/article/pii/S0925400514005358
Magnetic nanoparticle, EGFR, cancer cell, capturing
|[Precision Nanomedicine] Xinglu Huang, Fan Zhang, Yu Wang, Xiaolian Sun, Ki Young Choi, Dingbin Liu, Jin-sil Choi, Tae-Hyun Shin, Jinwoo Cheon, Gang Niu, and Xiaoyuan Chen*
Design Considerations of Iron-Based Nanoclusters for Noninvasive Tracking of Mesenchymal Stem Cell Homing
ACS Nano, 8(5), 4403-4414 (Apr 22, 2014) DOI : https://doi.org/10.1021/nn4062726
Stem-cell-based therapies have attracted considerable interest in regenerative medicine and oncological research. However, a major limitation of systemic delivery of stem cells is the low homing efficiency to the target site. Here, we report a serendipitous finding that various iron-based magnetic nanoparticles (MNPs) actively augment chemokine receptor CXCR4 expression of bone-marrow-derived mesenchymal stem cells (MSCs). On the basis of this observation, we designed an iron-based nanocluster that can effectively label MSCs, improve cell homing efficiency, and track the fate of the cells in vivo. Using this nanocluster, the labeled MSCs were accurately monitored by magnetic resonance imaging and improved the homing to both traumatic brain injury and glioblastoma models as compared to unlabeled MSCs. Our findings provide a simple and safe method for imaging and targeted delivery of stem cells and extend the potential applications of iron-based MNPs in regenerative medicine and oncology
|[Precision Nanomedicine] Tae-Hyun Shin, Jin-sil Choi, Seokhwan Yun, Il-Sun Kim, Ho-Taek Song, Youngmee Kim, Kook In Park, and Jinwoo Cheon
"T1 and T2 Dual-Mode MRI Contrast Agent for Enhancing Accuracy by Engineered Nanomaterials"
ACS Nano, 8 (4), 3393-3401 (Mar 27, 2014) DOI : http://pubs.acs.org/doi/abs/10.1021/nn405977t
MRI contrast agent, nanoparticle, dual-mode contrast agent, stem cell tracking
|[Precision Nanomedicine] Dongwon Yoo, Heeyeong Jeong, Seung-Hyun Noh, Jae-Hyun Lee, and Jinwoo Cheon
"Magnetically Triggered Dual Functional Nanoparticles for Resistance-Free Apoptotic Hyperthermia"
Angew. Chem. Int. Ed., 52 (49), 13047-13051 (Dec 2, 2013) DOI : http://onlinelibrary.wiley.com/doi/10.1002/anie.201306557/abstract
Magnetic hyperthermia, drug release, drug-resistance, cancer, dual function
|[Nanobio Interface] Mohammad Mehrmohammadi, Tae-Hyun Shin, Min Qu, Pieter Kruizinga,Ryan L. Truby, Jae-Hyun Lee, Jinwoo Cheon and Stanislav Y. Emelianov
"In vivo pulsed magneto-motive ultrasound imagingusing high-performance magnetoactive contrastnanoagents"
Nanoscale, 5 (22), 11179-11186 (Nov 21, 2013) DOI : http://pubs.rsc.org/en/Content/ArticleLanding/2013/NR/c3nr03669c#!divAbstract
Magneto-motive ultrasound imaging, ultrasound, magnetoactive, contrast agent
|[Nanobio Interface] Christine A. Falaschetti, Tatjana Paunesku, Jasmina Kurepa, Dhaval Nanavati, Stanley S. Chou, Mrinmoy De, MinHa Song,Jung-tak Jang, Aiguo Wu, Vinayak P. Dravid, Jinwoo Cheon, Jan Smalle, and Gayle E. Woloschak
"Negatively Charged Metal Oxide Nanoparticles Interact with the 20S Proteasome and Differentially Modulate Its Biologic Functional Effects"
ACS Nano, 7 (9), 7759-7772 (Aug 9, 2013) DOI : http://pubs.acs.org/doi/abs/10.1021/nn402416h
Iron oxide nanoparticle, TiO2, protein, ubiquitin-proteasome
|[Precision Nanomedicine] Jae-Hyun Lee, Ji-wook Kim and Jinwoo Cheon
"Magnetic Nanoparticles for Multi-Imaging and Drug Delivery"
Mol. Cells, 35 (4), 274-284 (Apr 30, 2013) DOI : https://link.springer.com/article/10.1007%2Fs10059-013-0103-0
Magnetic drug delivery, magnetic hyperthermia, nanoparticle, magnetic resonance imaging, multi-mode imaging
|[Precision Nanomedicine] Christian Preihs, Jonathan F. Arambula, Darren Magda, Heeyeong Jeong, Dongwon Yoo, Jinwoo Cheon, Zahid H. Siddik, and Jonathan L. Sessler*
"Recent Developments in Texaphyrin Chemistry and Drug Discovery"
Inorg. Chem., 52 (21), 12184-12192 (Apr 4, 2013) DOI : http://pubs.acs.org/doi/10.1021/ic400226g
This article is part of the Metals in Medicine and Health special issue.
|[Precision Nanomedicine] Jae-Hyun Lee, Kuan-Ju Chen, Seung-Hyun Noh, Mitch Andre Garcia, Hao Wang, Wei-Yu Lin, Heeyeong Jeong, Brian Junoh Kong, David B. Stout,Jinwoo Cheon, and Hsian-Rong Tseng
"On-Demand Drug Release System for In Vivo Cancer Treatment through Self-Assembled Magnetic Nanoparticles"
Angew. Chem. Int. Ed., 52 (16), 4384-4388 (Mar 20, 2013) DOI : http://onlinelibrary.wiley.com/doi/10.1002/anie.201207721/abstract
Supramolecular, nanoparticle, thermal heating, drug release, cancer