- [Nanobio Interface] Apr 30, 2019
Small, Clickable, and Monovalent Magnetofluorescent Nanoparticles Enable Mechanogenetic Regulation of Receptors in a Crowded Live-Cell Microenvironment
Minsuk Kwak†, Wonji Gu†, Heekyung Jeong, Hyunjung Lee, Jung-uk Lee, Minji An, Yong Ho Kim, Jae-Hyun Lee, Jinwoo Cheon*, and Young-wook Jun* († equally contributed)
Nano Lett., 19 (6), 3761-3769Multifunctional magnetic nanoparticles have shown great promise as next-generation imaging and pertu...
- [Evolutionary Nanomaterials] Oct 11, 2018
Activation of the Basal Plane in Two Dimensional Transition Metal Chalcogenide Nanostructures
Jae Hyo Han†, Hong Ki Kim†, Bongkwan Baek, Jeonghee Han, Hyun S. Ahn, Mu-Hyun Baik*, and Jinwoo Cheon* († equally contributed)
J. Am. Chem. Soc., 140 (42), 13663-13671
Achieving a molecular level understanding of chemical reactions on the surface of solid-stat...
- [Precision Nanomedicine] Jul 11, 2018
Three-Dimensional Brain-Like Microenvironments Facilitate the Direct Reprogramming of Fibroblasts into Therapeutic Neurons
Yoonhee Jin†, Jung Seung Lee†, Jin Kim, Sungjin Min, Soohyun Wi, Ji Hea Yu, Gyeong-Eon Chang, Ann-Na Cho, Yeeun Choi, Da-Hee Ahn, Sung-Rae Cho, Eunji Cheong, Yun-Gon Kim, Hyong-Pyo Kim, Yonghwan Kim, Dong Seok Kim, Hyun Woo Kim, Zhejiu Quan, Hoon-Chul Kang*, and Seung-Woo Cho* († equally contributed)
Nat. Biomed. Eng., 2, 522-539Biophysical cues can improve the direct reprogramming of fibroblasts into neurons that can be used f...
- [Precision Nanomedicine] Jan 29, 2018
Deep Learning Improves Prediction of CRISPR–Cpf1 Guide RNA Activity
Hui Kwon Kim†, Seonwoo Min†, Myungjae Song, Soobin Jung, Jae Woo Choi, Younggwang Kim, Sangeun Lee, Sungroh Yoon*, and Hyongbum (Henry) Kim* († equally contributed)
Nat. Biotechnol., 36 (3), 239-241We present two algorithms to predict the activity of AsCpf1 guide RNAs. Indel frequencies for 15,000...
- [Nanobio Interface] Feb 6, 2017
Distance-Dependent Magnetic Resonance Tuning as a Versatile MRI Sensing Platform for Biological Targets
Jin-sil Choi†, Soojin Kim†, Dongwon Yoo, Tae-Hyun Shin, Hoyoung Kim, Muller D. Gomes, Sun Hee Kim, Alexander Pines, and Jinwoo Cheon* († equally contributed)
Nat. Mater., 16 (5), 537-542Nanoscale distance-dependent phenomena, such as Forster resonance energy transfer, are important int...
- [Nanobio Interface] Jun 2, 2016
A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time
Daeha Seo†, Kaden M. Southard†, Ji-wook Kim, Hyun Jung Lee, Justin Farlow, Jung-uk Lee, David B. Litt, Thomas Haas, A. Paul Alivisatos, Jinwoo Cheon, Zev J. Gartner*, and Young-wook Jun* († equally contributed)
Cell, 165 (6), 1507-1518Tools capable of imaging and perturbing mechanical signaling pathways with fine spatiotemporal resol...
