Yonsei Advanced Science Institute

• Director
• Faculty & SAB
• Researchers & Students
• Administrative Staff

Faculty & SAB

• Professors
• SAB (Scientific Advisory Board)

• • Nanoscience & Nanomedicine
  • Jae-Hyun Lee (이재현)
  • jhyun_lee(at)yonsei.ac.kr

Education

• 2005 - 2011Ph.D. Chemistry, Yonsei University, Seoul, Korea
• 2003 - 2005M.S. Chemistry, Yonsei University, Seoul, Korea
• 1998 - 2002B.S. Chemistry, Yonsei University, Seoul, Korea

Professional Career

• 2018 - PresentAssistant Professor, Advanced Science Institute, Yonsei University, Seoul, Korea
• 2014 - 2017Post-doctoral fellow, Dept. of Chemistry and Chemical Biology, Harvard University
• 2012 - 2013Visiting post-doctoral fellow: Dept. of Physics & Astronomy, UCLA
• 2011 - 2012Postdoctoral Fellow, Center for Evolutionary Nanoparticles, Dept. of Chemistry, Yonsei University

Awards and Honors

• 2016Most cited Korean scientist in medicine, Dong-A Ilbo
• 2015First place, Nanotechnology Young Researcher Award, IOP Publishing
• 2013Delegate of Korea, 63rd Lindau Nobel Laureate Meeting
• 2011Sung-ki Jung Award, Yonsei University

Publications

Selected publications

Jae-Hyun Lee, Anqi Zhang, Siheng Sean You, and Charles M. Lieber
“Spontaneous internalization of cell penetrating peptide-modified nanowires into primary neurons” Nano Lett. 2016, 16, 1509.

Jae-Hyun Lee, Ji-wook Kim, Michael Levy, Albert Kao, Seung-hyun Noh, Dolores Bozovic, and Jinwoo Cheon
“Magnetic nanoparticles for ultrafast mechanical control of inner ear hair cells” ACS Nano 2014, 8, 6590.

Yunlong Zhao, Siheng Sean You, Anqi Zhang, Jae-Hyun Lee, Jinlin Huang, and Charles M. Lieber
“Scalable Ultrasmall Three-Dimensional Nanowire Transistor Probes for Intracellular Recording” Nature Nanotechnol. 2019, 14, 783.

Jae-Hyun Lee, Jung-tak Jang, Jin-sil Choi, Seung Ho Moon, Seung-hyun Noh, Ji-wook Kim, Jin-Gyu Kim, Il-Sun Kim, Kook In Park and Jinwoo Cheon

“Exchange-coupled magnetic nanoparticles for efficient heat induction" Nature Nanotech. 2011, 6, 418.

Mi Hyeon Cho, Eun Jung Lee, Mina Son, Jae-Hyun Lee, Dongwon Yoo, Ji-wook Kim, Seung Woo Park, Jeon-Soo Shin, and Jinwoo Cheon

"A magnetic switch for the control of cell death signalling in in vitro and in vivo systems" Nature Materials 2012, 11, 1038.

 

Publications

41. Minjae Ku, Joohee Kim, Jong-Eun Won, Wonkyu Kang, Young-Geun Park Jihun Park, Jae-Hyun Lee, Jinwoo Cheon, Hyun Ho Lee, and Jang-Ung Park
“Smart, Soft Contact Lens for Wireless Immunosensing of Cortisol” Sci. Adv., 2020, 6, eabb2891.

40. Hunter C.Davis, Sunghwi Kang, Jae-Hyun Lee, Tae-Hyun Shin, Harry Putterman, Jinwoo Cheon, Mikhail G.Shapiro
“Nanoscale Heat Transfer from Magnetic Nanoparticles and Ferritin in an Alternating Magnetic Field” Biophys. J. 2020, 118, 1502.

39. Sangyoon Paik, Gwangmook Kim, Sehwan Chang, Sooun Lee, Dana Jin, Kwang-Yong Jeong, I Sak Lee, Jekwan Lee, Hongjae Moon, Jaejun Lee, Kiseok Chang, Su Seok Choi, Jeongmin Moon, Soonshin Jung, Shinill Kang, Wooyoung Lee, Heon-Jin Choi, Hyunyong Choi, Hyun Jae Kim, Jae-Hyun Lee, Jinwoo Cheon, Miso Kim, Jaemin Myoung, Hong-Gyu Park, Wooyoung Shim
“Near-field Sub-diffraction Photolithography with an Elastomeric Photomask”Nat. Commun. 2020, 11, 805.

38. Jiuk Jang, Hyobeom Kim, Sangyoon Ji, Ha Jun Kim, Min Soo Kang, Tae Soo Kim, Jong-eun Won, Jae-Hyun Lee, Jinwoo Cheon, Kibum Kang, Won Bin Im, Jang-Ung Park
“Mechanoluminescent, Air-Dielectric MoS₂ Transistors as Active-Matrix Pressure Sensors for Wide Detection Ranges from Footsteps to Cellular Motions” Nano Lett. 2020, 20, 66.

37. Sangyoon Ji, Jiuk Jang, Jae Chul Hwang, Youngjin Lee, Jae-Hyun Lee*, and Jang-Ung Park
“Amorphous Oxide Semiconductor Transistors with Air Dielectrics for Transparent and Wearable Pressure Sensor Arrays” Adv. Mater. Technol. 2019, 1900928.

36. Yoonhee Jin, Jung-uk Lee, Eunna Chung, Kisuk Yang, Jin Kim, Ji-wook Kim, Jong Seung Lee, Ann-Na Cho, Taekyu Oh, Jae-Hyun Lee, Seung-Woo Cho and Jinwoo Cheon
“Magnetic Control of Axon Navigation in Reprogrammed Neurons” Nano Lett. 2019, 19, 6517.

35. Yunlong Zhao, Siheng Sean You, Anqi Zhang, Jae-Hyun Lee, Jinlin Huang, and Charles M. Lieber
“Scalable Ultrasmall Three-Dimensional Nanowire Transistor Probes for Intracellular Recording” Nature Nanotechnol. 2019, 14, 783.

34. Minsuk Kwak, Wonji Gu, Heekyung Jeong, Hyunjung Lee, Jung-uk Lee, Minji An, Yong Ho Kim, Jae-Hyun Lee, Jinwoo Cheon and Young-wook Jun
“Small, Clickable, and Monovalent Magnetofluorescent Nanoparticles Enable Mechanogenetic Regulation of Receptors in a Crowded Live-Cell Microenvironment” Nano Lett. 2019, 19, 3761.

33. Seokhwan Yun, Tae-Hyun Shin, Jae-Hyun Lee (co-first), Mi Hyeon Cho, Il-Sun Kim, Ji-wook Kim, Kwangsoo Jung, Jinwoo Cheon, and Kook In Park
“Design of Magnetically Labeled Cells (Mag-Cells) for In Vivo Control of Stem Cell Migration and Differentiation” Nano Lett. 2018, 18, 838.

32. Seung Ho Moon, Seung-hyun Noh, Jae-Hyun Lee, Tae-Hyun Shin, Yongjun Lim, and Jinwoo Cheon
“Ultrathin interface regime of core–shell magnetic nanoparticles for effective magnetism tailoring” Nano Lett. 2017, 17, 800.

31. Michael Levy, Adrian Molzon, Jae-Hyun Lee, Ji-wook Kim, Jinwoo Cheon, and Dolores Bozovic
“High-order synchronization of hair cell bundles” Sci. Rep. 2016, 6, 39116.

30. Mi Hyeon Cho, Seulmi Kim, Jae-Hyun Lee, Tae-Hyun Shin, Dongwon Yoo, and Jinwoo Cheon
“Magnetic tandem apoptosis for overcoming multidrug-resistant cancer” Nano Lett. 2016, 16, 7455.

29. Ji-wook Kim, Jae-Hyun Lee (co-first), Ji-Hyun Ma, Eunna Chung, Hongsuh Choi, Jinwoong Bok, and Jinwoo Cheon
“Magnetic force nanoprobe for direct observation of audio frequency tonotopy of hair cells” Nano Lett. 2016, 16, 3885.

28. Jae-Hyun Lee, Anqi Zhang, Siheng Sean You, and Charles M. Lieber
“Spontaneous internalization of cell penetrating peptide-modified nanowires into primary neurons” Nano Lett. 2016, 16, 1509.

27. Jae-Hyun Lee, Ji-wook Kim, Michael Levy, Albert Kao, Seung-hyun Noh, Dolores Bozovic, and Jinwoo Cheon
“Magnetic nanoparticles for ultrafast mechanical control of inner ear hair cells” ACS Nano 2014, 8, 6590.

26. Dongwon Yoo, Heeyeong Jeong, Seung-Hyun Noh, Jae-Hyun Lee, and Jinwoo Cheon
“Magnetically triggered dual functional nanoparticles for resistance-free apoptotic hyperthermia” Angew. Chem. Int. Ed. 2013, 52, 13047.

25. Mohammad Mehrmohammadi, Tae-Hyun Shin, Min Qu, Pieter Kruizinga, Ryan L. Truby, Jae-Hyun Lee, Jinwoo Cheon and Stanislav Y. Emelianov
“In vivo pulsed magneto-motive ultrasound imaging using high-performance magnetoactive contrast nanoagents” Nanoscale 2013, 5, 11179.

24. Jae-Hyun Lee, Ji-wook Kim, Jinwoo Cheon
“Magnetic nanoparticles for multi-imaging and drug delivery” Mol. Cells 2013, 35, 274.

23. Jae-Hyun Lee, Kuan-Ju Chen, Seung-Hyun Noh, Mitch André Garcia, Hao Wang, Wei-Yu Lin, Heeyeong Jeong, Brian Kong, Jinwoo Cheon and Hsian-Rong Tseng

  "On-demand drug release system for in vivo cancer treatment via self-assembled magnetic nanoparticles" Angew. Chem. Int. Ed. 2013, 52, 4384.

22. Jae Hyo Han, Sujeong Lee, Dongwon Yoo, Jae-Hyun Lee, Sohee Jeong, Jin-Gyu Kim and Jinwoo Cheon

   "Unveiling chemical reactivity and structural transformation of 2-dimensional layered nanocrystals" J. Am. Chem. Soc. 2013, 135, 3736.

21. Mi Hyeon Cho, Eun Jung Lee, Mina Son, Jae-Hyun Lee, Dongwon Yoo, Ji-wook Kim, Seung Woo Park, Jeon-Soo Shin, and Jinwoo Cheon

   "A magnetic switch for the control of cell death signalling in in vitro and in vivo systems" Nature Materials 2012, 11, 1038.

20. Seung-hyun Noh, Wonjun Na, Jung-tak Jang, Jae-Hyun Lee, Eun Jung Lee, Seung Ho Moon, Yongjun Lim, Jeon-Soo Shin, and Jinwoo Cheon

 "Nanoscale magnetism control via surface and exchange anisotropy for optimized ferrimagnetic hysteresis" Nano Lett. 2012, 12, 3716.

19. David Rowland, Yuttana Roongthumskul, Jae-Hyun Lee, Jinwoo Cheon, and Dolores Bozovic

"Magnetic actuation of hair cells" Appl. Phys. Lett. 2011, 99, 193701.

18. Dongwon Yoo, Jae-Hyun Lee, Tae-Hyun Shin and Jinwoo Cheon

"Theranostic magnetic nanoparticles" Acc. Chem. Res. 2011, 44, 863.

17. Jae-Hyun Lee, Jung-tak Jang, Jin-sil Choi, Seung Ho Moon, Seung-hyun Noh, Ji-wook Kim, Jin-Gyu Kim, Il-Sun Kim, Kook In Park and Jinwoo Cheon

“Exchange-coupled magnetic nanoparticles for efficient heat induction" Nature Nanotech. 2011, 6, 418.

16. Jin-sil Choi, Jae-Hyun Lee, Tae-Hyun Shin, Ho-Taek Song, Eung Yeop Kim, and Jinwoo Cheon,

“Self-confirming “AND” logic nanoparticles for fault-free MRI" J. Am. Chem. Soc. 2010, 132, 11015.

15. Courtney R. Thomas, Daniel P. Ferris, Jae-Hyun Lee, Eunjoo Choi, Mi Hyeon Cho, Eun Sook Kim, J. Fraser Stoddart, Jeon-Soo Shin, Jinwoo Cheon, and Jeffrey I. Zink

“Noninvasive remote-controlled release of drug molecules in vitro using magnetic actuation of mechanized nanoparticles” J. Am. Chem. Soc. 2010, 132, 10623.

14. Jae-Hyun Lee, Eun Sook Kim, Mi Hyeon Cho, Mina Son, Soo-In Yeon, Jeon-Soo Shin, and Jinwoo Cheon

“Artificial control of cell signaling and growth by magnetic nanoparticles” Angew. Chem. Int. Ed. 2010, 49, 5698.

13. Jae-Hyun Lee, Kyuri Lee, Seung Ho Moon, Yuhan Lee, Tae Gwan Park, Jinwoo Cheon

   "All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery" Angew. Chem. Int. Ed. 2009, 48, 4174.

12. Jung-tak Jang, Hyunsoo Nah, Jae-Hyun Lee, Seung Ho Moon, Min Gyu Kim, Jinwoo Cheon

“Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles” Angew. Chem. Int. Ed. 2009, 48, 1234.

11. Jinwoo Cheon, Jae-Hyun Lee

   "Synergistically integrated nanoparticles as multimodal probes for nanobiotechnology" Accounts Chem. Res. 2008, 41, 1630.

10. Young-wook Jun, Jae-Hyun Lee, Jinwoo Cheon

   "Chemical design of nanoparticle probes for high-performance magnetic resonance imaging" Angew. Chem. Int. Ed. 2008, 47, 5122.

9. Yong-Min Huh, Eun-Sook Lee, Jae-Hyun Lee, Young-wook Jun, Pyung-Hwan Kim, Chae-Ok Yun, Joo-hang Kim, Jin-Suck Suh, Jinwoo Cheon

   "Hybrid nanoparticles for magnetic resonance imaging of target-specific viral gene delivery" Adv. Mater. 2007, 19, 3109.

8. Young Ki Hahn, Zongwen Jin, Joo H. Kang, Eunkeu Oh, Min-Kyu Han, Hak-Sung Kim, Jung-tak Jang, Jae-Hyun Lee, Jinwoo Cheon, Seung Hyun Kim, Hae-Sim Park, Je-Kyun Park

  "Magnetophoretic immunoassay of allergen-specific IgE in an enhanced magnetic field gradient" Anal. Chem. 2007, 79, 2214.

7. Jae-Hyun Lee, Yong-Min Huh, Young-wook Jun, Jung-wook Seo, Jung-tak Jang, Ho-Taek Song, Sungjun Kim, Eun-Jin Cho, Ho-Geun Yoon, Jin-Suck Suh, Jinwoo Cheon

  "Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging" Nature Medicine 2007, 13, 95.

6. Jae-Hyun Lee, Young-wook Jun, Soo-In Yeon, Jeon-Soo Shin, Jinwoo Cheon

  "Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma" Angew. Chem. Int. Ed. 2006, 45, 8160.

5. Jae-Hyun Lee, Sun Bae Lee, Young-Wook Chang, Sung-In Kim, Jinwoo Cheon, Kyung-Hwa Yoo

  "DNA linker controlled single electron tunneling behavior of nanoparticle assembly" J. Appl. Phys. 2005, 98, 084315.

4.Yong-Min Huh, Young-wook Jun, Ho-Taek Song, Sungjun Kim, Jin-sil Choi, Jae-Hyun Lee, Sarah Yoon, Kyung-Sup Kim, Jeon-Soo Shin, Jin-Suck Suh, Jinwoo Cheon

  "In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals" J. Am. Chem. Soc. 2005, 127, 12387.

3. Young-wook Jun, Jae-Hyun Lee, Jin-sil Choi, Jinwoo Cheon

"Symmetry-controlled colloidal nanocrystals: nonhydrolytic chemical synthesis and shape determining parameters" J. Phys. Chem. B. 2005, 109, 14795.

2. Young-wook Jun, Yong-Min Huh, Jin-sil Choi, Jae-Hyun Lee, Ho-Taek Song, Sung Jun Kim, Sarah Yoon, Kyung-Sup Kim, Jeon-Soo Shin, Jin-Suck Suh, Jinwoo Cheon

"Nanoscale size effect of nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging (MRI)" J. Am. Chem. Soc. 2005, 127, 5732.

1. Jinwoo Cheon, Nam-Jung Kang, Sang-Min Lee, Jae-Hyun Lee, Ji-Hyun Yoon, Sang Jun Oh

"Shape evolution of single crystalline iron oxide nanocrystals” J. Am. Chem. Soc. 2004, 126, 1950.

 

List