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[Precision Nanomedicine] John W. Hickey†, Elizabeth K. Neumann†, Andrea J. Radtke, Jeannie M. Camarillo, Rebecca T. Beuschel, Alexandre Albanese, Elizabeth McDonough, Julia Hatler, Anne E. Wiblin, Jeremy Fisher, Josh Croteau, Eliza C. Small, Anup Sood, Richard M. Caprioli, R. Michael Angelo, Garry P. Nolan, Kwanghun Chung, Stephen M. Hewitt, Ronald N. Germain, Jeffrey M. Spraggins, Emma Lundberg, Michael P. Snyder, Neil L. Kelleher, and Sinem K. Saka* († equally contributed)
Spatial Mapping of Protein Composition and Tissue Organization: A Primer for Multiplexed Antibody-Based Imaging
Nat. Methods, 19 (3), 284-295 (Nov 22, 2021) DOI : https://doi.org/10.1038/s41592-021-01316-yTissues and organs are composed of distinct cell types that must operate in concert to perform physi... |
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[Precision Nanomedicine] Chang Yeol Lee†, Ismail Degani†, Jiyong Cheong†, Ralph Weissleder, Jae-Hyun Lee, Jinwoo Cheon*, and Hakho Lee* († equally contributed)
Development of Integrated Systems for On-Site Infection Detection
Acc. Chem. Res., 54 (21), 3991–4000 (Nov 2, 2021) DOI : https://doi.org/10.1021/acs.accounts.1c00498Abstract
The modern healthcare system faces an unrelenting threat from microorganisms, as evidence... |
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[Evolutionary Nanomaterials & Nanodevices] Mikhail Feofanov , Dominik Lungerich, Vladimir Akhmetov, and Konstantin Amsharov*
Synthesis of Dumbbell-Like DBATT Dimers**
ChemistrySelect, 6 (39), 10671-10673 (Oct 20, 2021) DOI : http://doi.org/10.1002/slct.202103363Herein we report a novel approach to a very interesting class of compounds containing two acene-base... |
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[Precision Nanomedicine] Hojeong Yu, Hoyeon Lee, Jiyong Cheong, Sang Won Woo, Juhyun Oh, Hyun-Kyung Oh, Jae-Hyun Lee, Hui Zheng, Cesar M. Castro, Yeong-Eun Yoo, Min-Gon Kim, Jinwoo Cheon, Ralph Weissleder, and Hakho Lee*
A Rapid Assay Provides On-Site Quantification of Tetrahydrocannabinol in Oral Fluid
Sci. Transl. Med, 13 (616), 1-10 (Oct 20, 2021) DOI : https://doi.org/10.1126/scitranslmed.abe2352Abstract
Tetrahydrocannabinol (THC), the primary psychoactive ingredient of cannabis, impairs cogni... [Yonhap News], [Hankook Ilbo], [NEWSIS] |
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[Precision Nanomedicine] Young Hun Kim†, Man Sup Kwak†, Bin Lee, Jae Min Shin, Sowon Aum, In Ho Park, Min Goo Lee, and Jeon-Soo Shin († equally contributed)
Secretory Autophagy Machinery and Vesicular Trafficking Are Involved in HMGB1 Secretion
Autophagy, 17 (9), 2345-2362 (Oct 5, 2021) DOI : http://doi.org/10.1080/15548627.2020.1826690Nuclear protein HMGB1 is secreted in response to various stimuli and functions as a danger-associate... |
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[Precision Nanomedicine] Myungjae Song†, Jung Min Lim†, Seonwoo Min, Jeong-Seok Oh, Dong Young Kim, Jae-Sung Woo, Hiroshi Nishimasu, Sung-Rae Cho, Sungroh Yoon, and Hyongbum Henry Kim* († equally contributed)
Generation of a More Efficient Prime Editor 2 by Addition of the Rad51 DNA-Binding Domain
Nat. Commun., 12 (1), 1-8 (Sep 23, 2021) DOI : http://doi.org/10.1038/s41467-021-25928-2Although prime editing is a promising genome editing method, the efficiency of prime editor 2 (PE2) ... |
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[Precision Nanomedicine] Su Kyeom Kim, Yu Heun Kim, Sewon Park, and Seung-Woo Cho*
Organoid Engineering with Microfluidics and Biomaterials for Liver, Lung Disease, and Cancer Modeling
Acta Biomater., 132, 37-51 (Sep 15, 2021) DOI : http://doi.org/10.1016/j.actbio.2021.03.002As life expectancy improves and the number of people suffering from various diseases increases, the ... |
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[Precision Nanomedicine] Jisoo Shin, Eun Hye Kang, Soojeong Choi, Eun Je Jeon, Jung Ho Cho, Donyoung Kang, Hyungsuk Lee, In Sik Yun*, and Seung-Woo Cho*
Tissue-Adhesive Chondroitin Sulfate Hydrogel for Cartilage Reconstruction
ACS Biomater. Sci. Eng., 7 (9), 4230-4243 (Sep 13, 2021) DOI : http://doi.org/10.1021/acsbiomaterials.0c01414Chondroitin sulfate (CS), the main component of cartilage extracellular matrix, has attracted attent... |
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[Precision Nanomedicine] Hyewon Jang†, Dong Hyun Jo†, Chang Sik Cho, Jeong Hong Shin, Jung Hwa Seo, Goosang Yu, Ramu Gopalappa, Daesik Kim, Sung-Rae Cho, Jeong Hun Kim*, and Hyongbum Henry Kim* († equally contributed)
Application of Prime Editing to the Correction of Mutations and Phenotypes in Adult Mice with Liver and Eye Diseases
Nat. Biomed. Eng, 6 (2), 181-194 (Aug 24, 2021) DOI : https://doi.org/10.1038/s41551-021-00788-9The use of prime editing—a gene-editing technique that induces small genetic changes without t... |
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[Precision Nanomedicine] Jin Kim†, Kyung-Tae Lee†, Jong Seung Lee, Jisoo Shin, Baofang Cui, Kisuk Yang, Yi Sun Choi, Nakwon Choi, Soo Hyun Lee, Jae-Hyun Lee, Yong-Sun Bahn*, and Seung-Woo Cho* († equally contributed)
Fungal Brain Infection Modelled in a Human-Neurovascular-Unit-on-a-Chip with a Functional Blood–Brain Barrier
Nat. Biomed. Eng., 5 (8), 830-846 (Aug 1, 2021) DOI : http://doi.org/10.1038/s41551-021-00743-8
The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet and n... |
